Vertebral osteophyte formation in experimental disc degeneration
نویسندگان
چکیده
منابع مشابه
Contribution of disc degeneration to osteophyte formation in the cervical spine: a biomechanical investigation.
Cervical spine disorders such as spondylotic radiculopathy and myelopathy are often related to osteophyte formation. Bone remodeling experimental-analytical studies have correlated biomechanical responses such as stress and strain energy density to the formation of bony outgrowth. Using these responses of the spinal components, the present study was conducted to investigate the basis for the oc...
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Symptomatic disc degeneration is a complex pathological condition that involves a cascade of events and is not totally understood. In this context, animal models gain an important role, allowing for better understanding of the degenerative process and therapeutic interventions. There are several models with different methods of evaluation of experimental disc degeneration (EDD), including imagi...
متن کاملSynovial lining macrophages mediate osteophyte formation during experimental osteoarthritis.
OBJECTIVE In human osteoarthritis (OA), various forms of pathology are observed. Besides cartilage damage and fibrosis, neogenesis of bone, osteophyte formation, also occurs. Osteophytes are thought to limit joint movement and cause pain. The objective of this study was to investigate whether synovial macrophages are involved in osteophyte formation in experimental OA, and if they are, to study...
متن کاملDo the disc degeneration and osteophyte contribute to the curve rigidity of degenerative scoliosis?
BACKGROUND The factors associated with lateral curve flexibility in degenerative scoliosis have not been well documented. Disc degeneration could result in significant change in stiffness and range of motion in lateral bending films. The osteophytes could be commonly observed in degenerative spine but the relationship between osteophyte formation and curve flexibility remains controversial. The...
متن کاملCounterpoint: Appropriately Ambiguous-The Disc Osteophyte Complex.
Why DOC? Cervical spondylosis is unique to the cervical spine because of the anatomy and presence of the uncovertebral joints and spinal cord. This is often manifest over several segments with mass effect on the ventral thecal sac and cord from ventral disease (DOC) and posterior ligamentous hypertrophy. On MR imaging, we are often faced with a low-signal, posterior extension of the disc margin...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1980
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780230309